Largest Covid-19 vaccine study yet finds links to health conditions

Vaccines that protect against severe illness, death and lingering long Covid-19 symptoms from a coronavirus infection were linked to small increases in neurological, blood, and heart-related conditions in the largest global vaccine safety study to date.

The rare events – identified early in the pandemic – included a higher risk of heart-related inflammation from mRNA shots made by Pfizer Inc, BioNTech SE, and Moderna Inc, and an increased risk of a type of blood clot in the brain after immunisation with viral-vector vaccines such as the one developed by the University of Oxford and made by AstraZeneca Plc.

The viral-vector jabs were also tied to an increased risk of Guillain-Barre syndrome, a neurological disorder in which the immune system mistakenly attacks the peripheral nervous system.

More than 13.5 billion doses of Covid vaccines have been administered globally over the past three years, saving over 1 million lives in Europe alone. Still, a small proportion of people immunised were injured by the shots, stoking debate about their benefits versus harms.

The new research, by the Global Vaccine Data Network, was published in the journal Vaccine last week.

The research looked for 13 medical conditions that the group considered “adverse events of special interest” among 99 million vaccinated individuals in eight countries, aiming to identify higher-than-expected cases after a Covid shot.

Myocarditis, or inflammation of the heart muscle, was consistently identified following a first, second and third dose of mRNA vaccines, the study found.

The highest increase in the observed-to-expected ratio was seen after a second jab with the Moderna shot. A first and fourth dose of the same vaccine was also tied to an increase in pericarditis, or inflammation of the thin sac covering the heart.

Researchers found a statistically significant increase in cases of Guillain-Barre syndrome within 42 days of an initial Oxford-developed ChAdOx1 or “Vaxzevria” shot that wasn’t observed with mRNA vaccines.

Based on the background incidence of the condition, 66 cases were expected – but 190 events were observed.

ChAdOx1 was linked to a threefold increase in cerebral venous sinus thrombosis, a type of blood clot in the brain, identified in 69 events, compared with an expected 21.

The small risk led to the vaccine’s withdrawal or restriction in Denmark and multiple other countries. Myocarditis was also linked to a third dose of ChAdOx1 in some, but not all, populations studied.

Possible safety signals for transverse myelitis – spinal cord inflammation – after viral-vector vaccines was identified in the study.

So was acute disseminated encephalomyelitis – inflammation and swelling in the brain and spinal cord – after both viral-vector and mRNA vaccines.

Seven cases of acute disseminated encephalomyelitis after vaccination with the Pfizer-BioNTech vaccine were observed, versus an expectation of two.

The adverse events of special interest were selected based on pre-established associations with immunisation, what was already known about immune-related conditions and preclinical research. The study didn’t monitor for postural orthostatic tachycardia syndrome, or POTS, that some research has linked with Covid vaccines.

Exercise intolerance, excessive fatigue, numbness and “brain fog” were among common symptoms identified in more than 240 adults experiencing chronic post-vaccination syndrome in a separate study conducted by the Yale School of Medicine. The cause of the syndrome isn’t yet known, and it has no diagnostic tests or proven remedies.

The Yale research aims to understand the condition to relieve the suffering of those affected and improve the safety of vaccines, said Harlan Krumholz, a principal investigator of the study, and director of the Yale New Haven Hospital Centre for Outcomes Research and Evaluation.

“Both things can be true,” Krumholz said in an interview. “They can save millions of lives, and there can be a small number of people who’ve been adversely affected.”

https://www.scmp.com/news/world/united-states-canada/article/3252387/largest-covid-19-vaccine-study-yet-finds-links-health-conditions

KNN MOH keeps pestering me to get jabbed again, will it ever stop????!!!

Roughly 50% of the people who have taken mRNA vaccines were to some extent damaged by them.

Pfizer CEO surreptitiously dropped in on OYK recently.....

S$140m of expired COVID-19 vaccines was 'insurance' to avoid catastrophic economic impact, more deaths: Ong Ye Kung

SINGAPORE: About 15 per cent of Singapore's COVID-19 vaccine doses worth S$140 million have expired, Health Minister Ong Ye Kung said in Parliament on Tuesday (Mar 21), calling it a price the country was prepared to pay.

"The expiry of unused vaccines was an insurance premium – the price we were prepared to pay to stave off the risk of catastrophic consequences," he added.

Mr Ong noted that before COVID-19 vaccines became available, Singapore resorted to implementing a "circuit breaker" in April 2020 in a bid to contain the pandemic.

"The two-month circuit breaker cost us around S$11 billion in terms of GDP loss. And we spent close to another S$60 billion over two financial years to cushion the hardship for businesses and workers, not to mention all the heartaches, the difficulties families had to go through," he said.

"Without vaccines, we would certainly have had to resort to further circuit breakers during the Delta and Omicron waves of late 2021 and then throughout 2022. But we did not have to, because the vaccines - we got them early, and they protected us.

"More importantly, our approach averted many deaths due to COVID-19 infections and protected Singaporeans against that catastrophic consequence."

Speaking during the debate on the White Paper on Singapore's response to COVID-19, the Health Minister said Singapore had "deliberately over-procured" to mitigate the uncertainty of selected vaccine candidates not working, and the possibility of supply chains being disrupted.

And this meant having spare vaccine stock, which would expire.

The White Paper, which drew on a review conducted by former head of civil service Peter Ho, concluded that Singapore's COVID-19 vaccine strategy paid off.

The government recognised “very early on” that vaccines were the most promising exit strategy and worked to secure early access, according to the White Paper which was published earlier this month.

This meant Singapore had to “place bets, at substantial cost, on potential game-changers” before trials were completed, it added.

As of Dec 31 last year, Singapore's mortality rate for COVID-19 was around 300 deaths per million, said Deputy Prime Minister Lawrence Wong in his closing speech later in the afternoon.

This was "much lower" compared to other countries with five or 10 times the mortality rate, he added.

The Ministry of Health (MOH) said last October that about 10 per cent of Singapore's COVID-19 vaccine stock had expired. Because of confidentiality agreements with vaccine suppliers, further details were not revealed then, said Mr Ong.

Giving an update on the figures on Tuesday, Mr Ong explained: "I would have preferred to be more transparent and forthcoming with the information. We have since discussed with the vaccine suppliers, and they have agreed we can reveal the total value of the expired vaccines, so long as we do not give further breakdowns of quantity that enable people to ... estimate the cost of each dose (of vaccine)."

Singapore has tried to donate spare vaccines but there have been no takers because of an oversupply of vaccines worldwide.

"Manufacturers have ramped up their production capacity and demand has been going down as the pandemic stabilises," Mr Ong said.

He added that while the percentage of expired vaccines is likely to rise to close to 25 per cent as more vaccines expire, it should thereafter "stabilise".

MULTI-FACETED VACCINE STRATEGY

Mr Ong stressed that Singapore must remain prepared in case a dangerous variant of concern emerges. And looking ahead, its vaccine strategy will involve a number of different aspects.

For one, MOH will maintain and "periodically refresh" an adequate stock of COVID-19 vaccines, he said.

This will ensure the continued protection of the elderly and vulnerable as needed, as well as facilitate a rapid response should there be a major or more severe pandemic wave.

In addition, Singapore will maintain a "network" of vaccination centres - primary care clinics, polyclinics and a "baseline footprint" of between five to 10 Joint Testing and Vaccination Centres, said Mr Ong. This will allow booster doses to be given to people aged 50 and above as well as the medically vulnerable, within three weeks, if needed.

Singapore is also negotiating agreements to secure early access to vaccines against other pathogens with pandemic potential, added Mr Ong. It will also invest in vaccine research and development.

There are plans to have six vaccine manufacturing plants in Singapore, he revealed. Singapore will also continue to do its part to strengthen global health security, supporting fair and equitable access to vaccines.

https://www.channelnewsasia.com/singapore/expired-covid-19-vaccine-140-million-dollars-insurance-premium-white-paper-debate-3362376

Pfizer admits in European parliament that vaccines were never meant to prevent transmission:

Pfizer Tells Federal Judge that Pfizer Owns the Federal Government and Is thereby Immune to Normal Contract Law

Pfizer affirms that its agreement with Washington under “Other Transaction Authority” permits Pfizer to violate clinical trial regulations and federal laws protecting the public.

In other words, Pfizer has legal authority to commit fraud that kills people. https://www.theepochtimes.com/pfizer-moves-to-dismiss-lawsuit-from-covid-19-vaccine-trial-citing-prototype-agreement_4481422.html As I have explained on many occasions, the US government is privatized. It is run by private interests whose representatives are found on the SEC, FDA, EPA, Federal Reserve, and all other regulatory agencies. As George Stigler made clear 60 years ago, the US regulatory agencies are captured by the industries they are supposed to regulate. The power of private interests also comes from the fact that private interests are the financers of political campaigns. Every elected official—House, Senate, President—and every state and local official knows he/she is in office because of the campaign contributions. This means that elected officials are responsible to their donors, not to the voters. The power of private interests was reinforced by the US Supreme Court decision that gave essentially unlimited ability to corporations to purchase government to serve their interests. This is the real picture of today’s United States. The US is a country that can only serve private interests, never the public interest, itself a hard interest to define in a country in which identity politics is pervasive. In America today, the public interest is “whose interest?”Multiculturialism can never result in a united interest. Today there are an array of interests trying to have it all while suppressing other interests. The feminists, once a powerful force, are losing to the “transgendered.” Even former feminist heros are now cancelled and deplatformed. White Americans, branded “aversive racists,” have lost out to blacks who have been granted legal preferences, thus violating the 14th Amendment to the US Constitution which was passed for the explicit purpose of establishing the equal protection of law. Formerly sacrosanct heterosexuals now answer to formerly criminal homosexuals and are required to take “sensitivity training” to learn deference to homosexuals, preferred minorities, and transgendered claimants. Today the discrimination is against the white heterosexual male who is labeled a “domestic terrorist” unless he joins in the persecution of white heterosexual males and did not vote for Donald Trump. The US Democrat Party has defined its rival, the Republican Party, as the party of white supremacists, the party of “Trump deplorables.” The society that exists is the US today is so split that it no longer constitutes a country. There is NO UNIFYING BELIEF OR PRINCIPLE. The United States has become a Tower of Babel, and the Americans are unaware of who brought this affliction upon them and the societal collapse that it is bringing.

https://www.paulcraigroberts.org/2022/05/23/pfizer-tells-federal-judge-that-pfizer-owns-the-federal-government-and-is-thereby-immune-to-normal-contract-law/

CHD Says Pfizer and FDA Dropped Data Bombshell on COVID Vaccine Consumers

Washington, DC, March 03, 2022 (GLOBE NEWSWIRE) -- In a 55,000-page set of documents released on Tuesday, the U.S. Food and Drug Administration’s (FDA’s) Center for Biologics Evaluation and Research (CBER) is for the first time allowing the public to access data Pfizer submitted to FDA from its clinical trials in support of a COVID-19 vaccine license. This follows U.S. District Judge Mark T. Pittman’s decision on January 6 to deny the request from the FDA to suppress the data for the next 75 years which the agency claimed was necessary, in part, because of its “limited resources.”

A 38-page report included in the documents features an Appendix, “LIST OF ADVERSE EVENTS OF SPECIAL INTEREST,” that lists 1,291 different adverse events following vaccination. The list includes acute kidney injury, acute flaccid myelitis, anti-sperm antibody positive, brain stem embolism, brain stem thrombosis, cardiac arrest, cardiac failure, cardiac ventricular thrombosis, cardiogenic shock, central nervous system vasculitis, death neonatal, deep vein thrombosis, encephalitis brain stem, encephalitis hemorrhagic, frontal lobe epilepsy, foaming at mouth, epileptic psychosis, facial paralysis, fetal distress syndrome, gastrointestinal amyloidosis, generalized tonic-clonic seizure, Hashimoto's encephalopathy, hepatic vascular thrombosis, herpes zoster reactivation, immune-mediated hepatitis, interstitial lung disease, jugular vein embolism, juvenile myoclonic epilepsy, liver injury, low birth weight, multisystem inflammatory syndrome in children, myocarditis, neonatal seizure, pancreatitis, pneumonia, stillbirth, tachycardia, temporal lobe epilepsy, testicular autoimmunity, thrombotic cerebral infarction, Type 1 diabetes mellitus, venous thrombosis neonatal, and vertebral artery thrombosis among 1,246 other medical conditions following vaccination.

“This is a bombshell,” said Children’s Health Defense (CHD) president and general counsel Mary Holland. “At least now we know why the FDA and Pfizer wanted to keep this data under wraps for 75 years. These findings should put an immediate end to the Pfizer COVID vaccines. The potential for serious harm is very clear, and those injured by the vaccines are prohibited from suing Pfizer for damages.”

The U.S. government has already purchased 50 million doses of the Pfizer vaccine intended for children under five years of age to be delivered by April 30, 2022 although the FDA has yet to grant an Emergency Use Authorization (EUA) for this age group. The risk of serious injury or death from COVID to healthy children is practically nil and so far, the vaccine is not effective when used in young children.

According to The Guardian, “Pfizer made nearly $37bn (£27bn) in sales from its Covid-19 vaccine last year – making it one of the most lucrative products in history – and has forecast another bumper year in 2022, with a big boost coming from its Covid-19 pill Paxlovid.” President Biden advertised Paxlovid in his State of the Union address on Tuesday, the same day the Pfizer data was released to the public. “We’re launching the ‘Test to Treat’ initiative so people can get tested at a pharmacy, and if they’re positive, receive antiviral pills on the spot at no cost,” Biden said during his speech.

From mid-December, 2020 through February 18, 2022, the U.S. government’s database, the Vaccine Adverse Events Reporting System (VAERS), has received 1,134,984 reports of adverse events, including 24,402 deaths, following COVID vaccination. Additionally, there have been 4,021 cases of myocarditis and pericarditis in the U.S. with 2,475 cases associated with Pfizer, 1,364 cases with Moderna and 171 cases with J&J’s COVID vaccine. These include 643 reports of myocarditis and pericarditis in children aged 12 to 17.

“It would be criminal to expose infants and young children to this extremely risky product,” said Holland. “VAERS data show the catastrophic health impacts the vaccine is having on millions of people, yet Pfizer and other vaccine makers are raking in billions of dollars with no fear of being held accountable for injuries and deaths from their vaccines.”

The FDA’s attempt to suppress these data in support of the pharmaceutical industry’s bottom line isn’t a new phenomenon in this country’s public health system. For more information on pharmaceutical corruption and the tight relationship the industry has with government regulatory agencies, read The Real Anthony Fauci: Bill Gates, Big Pharma and the Global War on Democracy and Public Health by CHD Chair and lead counsel Robert F. Kennedy, Jr.

https://www.globenewswire.com/news-release/2022/03/03/2396681/0/en/CHD-Says-Pfizer-and-FDA-Dropped-Data-Bombshell-on-COVID-Vaccine-Consumers.html

Pfizer made to release its vaccine trial data, possible side effects listed span 9 whopping pages!!!!!!

Pfizer paid 2.8 million USD to the US government seeking priority review of its vaccine for use on children under 16 years old - did it also do the same here in Singapore?

Fann Wong intends to have her son vaccinated, because she trusts the government lol

Singapore approves Pfizer COVID vaccine for kids aged 5 to 11

SINGAPORE — Singapore's Health Sciences Authority (HSA) on Friday (10 December) approved the use of the paediatric doses of the Pfizer-BioNTech COVID-19 vaccine for children aged 5 to 11, with vaccinations for the age group planned to begin before end-2021.

The Ministry of Health (MOH) said in a press release that it will work with the Ministry of Education (MOE) and the Early Childhood Development Agency (ECDA) to roll out vaccinations for the school-going age group.

More details will be announced by the MOE and ECDA "shortly", the ministry added.

The Pfizer vaccine will be the first COVID-19 vaccine the HSA has granted approval for use in Singapore for those aged 5 to 11, said the MOH, adding that the expert committee on COVID-19 vaccines has recommended its use for the age group.

The committee "has assessed that the benefits of the Pfizer-BioNTech/Comirnaty vaccine outweigh the risks when used in a paediatric dosage for children aged 5 to 11 years, especially given ongoing community transmission and the emergence of the Omicron variant", the ministry added.

In line with the committee's recommendations, children with moderate to severe chronic medical conditions should be prioritised for access to the vaccine.

Similar to the practice in the US, the recommended dosage of the Pfizer vaccine for the age group in Singapore is one-third of that used in those aged 12 and above.

Younger children would be given two paediatric doses, 10 micrograms each, that is spaced at least 21 days apart.

90.7% efficient based on trials; Pfizer jab registered in S'pore

The HSA in a separate release on Friday said it had reviewed the clinical data for this subgroup which showed that the paediatric dose" induced a robust immune response that was comparable" to that with 30 micrograms observed in those aged 16 to 25.

"The vaccine efficacy was estimated to be 90.7 per cent based on an ongoing Phase 2/3 study in children aged 5 to 11 years," it added. A total of 2,186 participants were randomised to receive either the vaccine or the placebo: 1,450 received the vaccine and 736 received the placebo.

The overall safety profile of the vaccine in the age group, based on safety follow-up data with a median duration of two months after vaccination, was observed to be comparable to that seen in adults and adolescents, said the HSA.

Side effects such as injection site pain, fatigue, headache, chills, and fever were generally reported less frequently and were milder in severity in the children compared to adolescents. These side effects generally resolved on their own within a few days.

While there were no reports of myocarditis, pericarditis or anaphylaxis observed in the clinical study, the HSA said it has required Pfizer-BioNTech to continue to provide information on the safety and efficacy of the vaccine in this younger age group, given the relatively small number of subjects in the clinical trial, and the potential risks of these rare adverse events.

The HSA also said that Pfizer-BioNTech had submitted an application to transition the current interim authorisation for the Comirnaty vaccines under the pandemic special access route to product registration.

The authority added that it has assessed the data accrued to-date on the manufacturing process and has concluded that the clinical studies are sufficient to register the vaccine, with effect from Friday.

Authorities had last month announced that Singapore has signed a new supply agreement with Pfizer for its COVID-19 vaccine, including doses for children.

Singapore's booster vaccination drive extended

Meanwhile, from next Tuesday, those aged 18 to 29 here can get their mRNA booster shots, provided at least five months have passed since their primary doses.

The mRNA vaccines – developed by Pfizer and Moderna – under Singapore's booster vaccination programme can be used interchangeably as boosters.

"While the primary series vaccinations provide excellent protection against severe disease, there is evidence of waning protection against infection over time, albeit at a slower pace in younger persons," said the MOH.

Eligible individuals will be invited to make an appointment for their booster dose via a short message service (SMS) with a personalised booking link that will be sent to their registered mobile number.

As of Thursday, the total number of individuals who have completed their full regimen or received two doses of COVID-19 vaccines is 96 per cent of the eligible population.

Among the total population, 87 per cent have done so, while 87 per cent has received at least one dose, and 30 per cent has received their booster shots.

While encouraging, the MOH said more people need to be vaccinated and boosted, especially given the emergence of Omicron.

"Vaccinations and boosters are the best protection against an unknown and highly transmissible COVID-19 variant," the ministry noted.

https://sg.news.yahoo.com/singapore-approves-pfizer-vaccine-for-kids-aged-5-to-11-155207412.html

Pfizer CEO predicts a fourth shot might be needed in light of Omicron variant

The CEO of Pfizer Inc has said that a fourth dose of coronavirus vaccine might be needed for better protection against the Omicron variant, as initial studies have shown that it could undermine antibody protection with two doses.

Albert Bourla said the company was waiting to see real-world data to determine whether additional doses would be required specifically for Omicron.

The pressure for booster jabs has increased on governments around the world with the discovery of the new variant.

Earlier on Wednesday, Pfizer released findings from an initial lab study that showed that two vaccine doses had a lower ability to fight omicron compared to other variants, while a third jab improved protection significantly. The findings were in line with the results of a study carried out in South Africa by doctors earlier this week.

However, since it was an early lab study, it was based on a lab-created copy of the variant. Researchers say more needs to be understood about the omicron variant.

Mr Bourla said the third dose should be rolled out as soon as possible and added that it could provide the needed protection against another wave of infections.

“A third dose will give very good protection I believe,” Mr Bourla said, adding that treatments such as Pfizer’s oral antiviral pill Paxlovid will help prevent hospitalisations and control Covid during winter.

He had said even earlier that a fourth shot may be needed, but estimated that it would be required only around a year after the third dose. But now, he said that it could be needed sooner.

“With Omicron, we need to wait and see because we have very little information. We may need it faster,” he said.

Mr Bourla added that the company was evaluating whether any adjustments were needed to the current vaccine to provide better protection against the omicron variant or other future variants, or whether an entirely different vaccine would be needed to target it.

https://sg.news.yahoo.com/pfizer-ceo-predicts-fourth-shot-071255793.html